Centre for Dengue Research

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Dengue viral infections are one of the most important mosquito borne viral infections in the world, infecting approximately 390 million individuals a year. Therefore, carrying out relevant and cutting edge research this area in order to come up with a long lasting solution, is the most urgent priority at this hour.

Vision and Mission

To conduct high quality, with high scientific standard, to find long lasting solutions to reduce the morbidity and mortality associated with dengue.

Objectives

a. Drug development

i. Develop drugs that can be used to treat dengue

ii. Determine the efficacy of an existing or new drugs to treat dengue by conducting, scientific clinical trials which are unbiased to test for novel or existing drugs for dengue

b. Vaccine related research Identity T cell and antibody correlates of protection for dengue in order to determine correlates of protection against dengue

c. Epidemiological research Development of proper surveillance system to monitor changes in the dengue incidence and also the circulating DENV serotypes in urban, suburban and rural populations in Sri Lanka

d. Research related to development of diagnostics and clinical characteristics of dengue

i. Development of dengue diagnostics and co-ordination of institutes to identify the true burden of dengue in hospitalized patients by carrying out diagnostics to confirm dengue and similar illnesses (Hanta virus, ZIKA, WNV, Influenza) during dengue epidemics

ii. To understand factors that lead to fluid leakage and prediction or prevention of leakage

Advisory Panel

  • Dr. Chandima Jeewandara – Department of Family Medicine, University of Sri Jayewardenepura
  • Emeritus Professor Krishan Deheragoda – University of Sri Jayewardenepura – Invited
  • Prof. Graham Ogg – University of Oxford
  • Prof. Nicole Zitzmann – University of Oxford y Prof. Ng Mah Lee – National University of Singapore
  • Prof. Marilyn Sue O Hara – University of Illinois y Senior Assistant Bursar – Invited

Facilities Available

Tissue culture facilities, Magnetic cytokine bead array analysis: Magpix, Liquid nitrogen storage, 12 Colour and 4 Colour flowcytometry, ELISpot facilities, Digital Inkjet Plotter-Printer, 5 Colour real time PCR, DNA and RNA quantification